Review Article
A Meta-Analysis of the Association between DNMT1 Polymorphisms and Cancer Risk
Table 4
Meta-analysis results of the association between DNMT1 rs2228612 (A/G) polymorphism and cancer risk.
| Genetic model | Heterogeneity test | Statistical model | Test for overall effect | (%) | | OR (95% CI) | |
| GG versus AA | 19.20 | 0.292 | F | 1.20 (0.97–1.49) | 0.088 | AG versus AA | 60.30 | 0.039 | R | 0.81 (0.61–1.08) | 0.156 | (GG + AG) versus AA | 62.7 | 0.030 | R | 0.87 (0.66–1.14) | 0.310 | GG versus (AA + AG) | 11.50 | 0.340 | F | 1.29 (1.06–1.56) | 0.009 | G allele versus A allele | 58.70 | 0.046 | R | 1.00 (0.83–1.20) | 0.980 |
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R: random effect model; F: fixed effect model.
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