A Meta-Analysis of the Association between DNMT1 Polymorphisms and Cancer Risk

Table 4

Meta-analysis results of the association between DNMT1 rs2228612 (A/G) polymorphism and cancer risk.

Genetic model	Heterogeneity test		Statistical model	Test for overall effect
	(%)			OR (95% CI)
GG versus AA	19.20	0.292	F	1.20 (0.97–1.49)	0.088
AG versus AA	60.30	0.039	R	0.81 (0.61–1.08)	0.156
(GG + AG) versus AA	62.7	0.030	R	0.87 (0.66–1.14)	0.310
GG versus (AA + AG)	11.50	0.340	F	1.29 (1.06–1.56)	0.009
G allele versus A allele	58.70	0.046	R	1.00 (0.83–1.20)	0.980

R: random effect model; F: fixed effect model.