Research Article
Safety Assessment and Comparison of Sodium Selenite and Bioselenium Obtained from Yeast in Mice
Table 6
The experimental results of bio-Se in sperm aberration test.
| Category | Dose (mg/kg) | Number of tested animals | Sperm count | Distortion sperm count | Sperm aberration rate (%) |
| 1/2LD50 | 1.47 | 10 | 10 × 1000 | 243 | 2.43 ± 0.532 | 1/4LD50 | 2.95 | 10 | 10 × 1000 | 283 | 2.83 ± 0.547 | 1/2LD50 | 5.89 | 10 | 10 × 1000 | 252 | 2.52 ± 0.475 | Negative control group | Distilled water | 10 | 10 × 1000 | 269 | 2.69 ± 0.658 | Positive control group | Cyclophosphamide (40 mg/kg) | 10 | 10 × 1000 | 445 | 4.45 ± 1.158 |
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Note. indicates that there are significant differences () with negative control group.
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