Safety Assessment and Comparison of Sodium Selenite and Bioselenium Obtained from Yeast in Mice

Table 9

Effects of 30-day subchronic toxicity test on organ coefficient of mice using sodium selenite.

Group	Heart/bw%; (mean ± SD)	Liver/bw%; (mean ± SD)	Spleen/bw%; (mean ± SD)	Kidney/bw%; (mean ± SD)
Negative control	0.35 ± 0.05	4.36 ± 0.38	0.23 ± 0.03	0.68 ± 0.05
Low dose group	0.36 ± 0.03	4.70 ± 0.38	0.22 ± 0.02	0.71 ± 0.06
Middle dose group	0.39 ± 0.04	5.03 ± 0.62	0.19 ± 0.01	0.74 ± 0.04
High dose group	0.43 ± 0.06	5.41 ± 0.78	0.16 ± 0.01	0.79 ± 0.07

Note. Letters in common in the same column do not present significant difference (), for example, A and A, b and b. Same letters in upper and lower case or different letters in lower-case in the same column present significant difference (), for example, B and b, b and c. Different letters in uppercase or different letters in uppercase and lowercase present extremely significant difference (), for example, A and B, B and c.