Cytotoxicity and Antimicrobial Activity of Oral Rinses In Vitro
Table 2
LC50 of oral rinse and oral rinse additives.
(a)
#1
#2
#3
#4
#5
#6
#7
#8
#9
#10
#11
#12
LC50
—
—
62.3%
23.7%
19.6%
7.0%
5.8%
6.9%
12.4%
11.9%
6.8%
7.4%
Gingival fibroblasts were exposed to a series of dilutions of oral rinses, and LC50 was analyzed after 2 minutes. Values show the percentage of dilution based on the original formulation of oral rinse. For oral rinses #1 and #2, more than 50% of the cells remained vital after exposure, and, therefore, no LC50 was analyzed, indicated with —.
(b)
EtOH
CHX
CPC
PEG
SDS
SF 500 ppm
LC50
25.2%
0.02%
0.06 mM
45.7%
0.36%
0%
Cell cultures of gingival fibroblasts were exposed to various oral rinse additives. LC50 was analyzed after 2 minutes of exposure time.
