Association between Single Nucleotide Polymorphisms in Vitamin D Receptor Gene Polymorphisms and Permanent Tooth Caries Susceptibility to Permanent Tooth Caries in Chinese Adolescent

Table 3

Summary of allele and genotype frequencies in 12-year-old adolescents.

VDR gene polymorphisms (rs number)		Total	Caries experience; ()	Caries-free; ()	X^2	value	OR (95% CI)	Power (%)
Bsm I (rs1544410)	AA	0	0	0	0.448	0.503
	AG	67 (16.75)	36 (18)	31 (15.5)
	GG	333 (83.25)	164 (82)	169 (84.5)
	Carriage of allele A		36 (18)	31 (15.5)	0.448	0.503	1.197 (0.707–2.026)
	A	67 (8.375)	36 (9)	31 (7.75)	0.407	0.523	1.177 (0.713–1.944)	9.8
	G	733 (91.625)	364 (91)	369 (92.25)
Taq I (rs731236)	CC	329 (82.25)	171 (85.5)	158 (79)	2.894	0.089
	CT	71 (17.75)	29 (14.5)	42 (21)
	TT	0	0	0
	Carriage of allele T		29 (14.5)	42 (21)	2.894	0.089	0.638 (0.379–1.073)
	C	729 (91.125)	371 (92.75)	358 (89.5)	2.612	0.106	1.501 (0.915–2.462)	47.5
	T	71 (8.875)	29 (7.25)	42 (10.5)
Apa I (rs7975232)	AA	57 (14.25)	33 (16.5)	24 (12)	2.898	0.235
	AC	164 (41)	85 (42.5)	79 (39.5)
	CC	179 (44.75)	82 (41.0)	97 (48.5)
	Carriage of allele A		118 (59)	103 (51.5)	2.275	0.131	1.355 (0.913–2.012)
	Carriage of allele C		167 (83.5)	176 (88)	1.657	0.198	0.69 (0.391–1.216)
	A	278 (34.75)	151 (37.75)	127 (31.75)	3.175	0.075	1.304 (0.974–1.745)	43.1
	C	522 (65.25)	249 (62.25)	273 (68.25)
Fok I (rs10735810)	CC	151 (37.75)	86 (43.0)	65 (32.5)	17.813	0.000
	CT	182 (45.5)	96 (48.0)	86 (43.0)
	TT	67 (16.75)	18 (9)	49 (24.5)
	Carriage of allele C		182 (91)	151 (75.5)	17.229	0.000	3.281 (1.834–5.870)
	Carriage of allele T		114 (57)	135 (67.5)	4.692	0.03	0.638 (0.425–0.959)
	C	484 (60.5)	268 (67)	216 (54)	14.144	0.000	1.730 (1.299–2.303)	97.1
	T	316 (39.5)	132 (33)	184 (46)