Research Article

Bone Regeneration Using N-Methyl-2-pyrrolidone as an Enhancer for Recombinant Human Bone Morphogenetic Protein-2 in a Rabbit Sinus Augmentation Model

Table 1

Histomorphometric analysis in total augmentation (mean ± SD; mm2).

BCP ()BMP ()BMP/NMP ()

TA16.01 ± 3.0119.07 ± 4.4220.05 ± 4.51
1.28 ± 0.521.50 ± 0.721.94 ± 0.69
6.69 ± 1.436.92 ± 1.356.87 ± 1.28
8.04 ± 1.7110.66 ± 3.7211.24 ± 4.07

No statistical difference among groups (); TA, total augmented area; , new bone area within TA; , residual graft material area within TA; , nonmineralized tissue area within TA.