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BioMed Research International
Volume 2017, Article ID 4191670, 10 pages
Review Article

Efficacy and Safety of Cerebrolysin for Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials

Department of Neurosurgery, Shanghai Institute of Neurosurgery, PLA Institute of Neurosurgery, Changzheng Hospital, Second Military Medical University, Shanghai, China

Correspondence should be addressed to Junyu Wang; moc.361@8002emorej and Lijun Hou; moc.621@zcuohnujil

Received 16 March 2017; Accepted 9 May 2017; Published 5 June 2017

Academic Editor: John H. Zhang

Copyright © 2017 Danfeng Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

S1 Fig: Risk of bias graph.

S2 Fig: Risk of bias summary.

S1 Table: Original data of efficacy and safety outcomes in included studies. AE, adverse event; ARAT, Action Research Arm Test; BI, Barthel Index; CNS, Canadian Neurological Scale; GCS, Glasgow Coma Scale; GOS, Glasgow Outcome Scale; IQR, interquartile range; MMSE, Mini-Mental State Examination; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SAE, serious adverse event; SD, standard deviation; SST, syndrome short test; UNSS, Unified Neurological Stroke Scale. *Post-baseline mRS data were not a vailable for five patients in the cerebrolysin group. Data expressed as mean (95% CI); Data expressed as median (IQR).

  1. Supplementary Material