Schisandrin B Prevents Hind Limb from Ischemia-Reperfusion-Induced Oxidative Stress and Inflammation via MAPK/NF-κB Pathways in Rats

Figure 4

ScB reduced activation of p38, ERK1/2, JNK, and NF-κB in the skeletal muscle following hind limb I/R. (a, b) Representative immunoblots and densitometric analysis of p-p38MAPK, total p38, and GAPDH in the ischemic skeletal muscle after 24 h reperfusion. (c, d) Representative immunoblots and densitometric analysis of p-ERK1/2, total ERK1/2, and GAPDH in the ischemic skeletal muscle after 24 h reperfusion. (e, f) Representative immunoblots and densitometric analysis of p-JNK, total JNK, and GAPDH in the ischemic skeletal muscle after 24 h reperfusion. (g, h) Representative immunoblots and densitometric analysis of NF-κB p65 and GAPDH in the ischemic skeletal muscle after 24 h reperfusion. versus sham, versus I/R, per group.

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