Research Article

Inhibitory Activities of Stauntonia hexaphylla Leaf Constituents on Rat Lens Aldose Reductase and Formation of Advanced Glycation End Products and Antioxidant

Table 3

Inhibitory effect of compounds isolated from Stauntonia hexaphylla leaves on advanced glycation end products (AGEs) formation.

CompoundsIC50

3-(3,4-Dihydroxyphenyl)-propionic acid (1)184.06 ± 17.62
Chlorogenic acid (2)>1000
Neochlorogenic acid (3)115.07 ± 10.47
Calceolarioside B (4)>1000
Luteolin-3′-O-β-D-glucopyranoside (5)117.80 ± 11.46
Quercetin-3-O-β-D-glucopyranoside (6)>1000
Luteolin-7-O-β-D-glucopyranoside (7)>1000

820.44 ± 79.42

IC50 value was defined as a mean ± SEM of half-maximal inhibitory concentration from three independent experiments performed in duplicate.
is the positive control for advanced glycation end products.