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BioMed Research International
Volume 2017, Article ID 4281629, 7 pages
https://doi.org/10.1155/2017/4281629
Research Article

Incremental Value of Plaque Enhancement in Patients with Moderate or Severe Basilar Artery Stenosis: 3.0 T High-Resolution Magnetic Resonance Study

1Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China
2Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
3MR R&D, Siemens Healthineers, Los Angeles, CA, USA
4Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China

Correspondence should be addressed to Kuncheng Li; gro.psohwx@gnehcnukil

Received 28 March 2017; Revised 7 June 2017; Accepted 16 July 2017; Published 17 September 2017

Academic Editor: Dobrin Vassilev

Copyright © 2017 Wanqian Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aim. To investigate the clinical relevance of plaque’s morphological characteristics and distribution pattern using 3.0 T high-resolution magnetic resonance imaging (HRMRI) in patients with moderate or severe basilar artery (BA) atherosclerosis stenosis. Materials and Methods. Fifty-seven patients (33 symptomatic patients and 24 asymptomatic patients) were recruited for 3.0 T HRMRI scan; all of them had >50% stenosis on the BA. The intraplaque hemorrhage (IPH), contrast-enhancement pattern, and distribution of BA plaques were compared between the symptomatic and asymptomatic groups. Factors potentially associated with posterior ischemic stroke were calculated by multivariate analyses. Results. Enhancement of BA plaque was more frequently observed in symptomatic than in asymptomatic patients (27/33, 81.8% versus 11/24, 45.8%; ). In multivariate regression analysis, plaque enhancement (OR = 7.193; 95% CI: 1.880–27.517; ) and smoking (OR = 4.402; 95% CI: 2.218–15.909; ) were found to be independent risk factors of posterior ischemic events in patients with BA stenosis >50%. Plaques were mainly distributed at the ventral site (39.3%) or involved more than two arcs (21.2%) in the symptomatic group but were mainly distributed at left (33.3%) and right (25.0%) sites in the asymptomatic group.