Research Article

Identification of Key Pathways and Genes in Advanced Coronary Atherosclerosis Using Bioinformatics Analysis

Table 3

Biological process (GO) enrichment analysis in networks.

Expression#Pathway IDPathway descriptionObserved gene countFalse discovery rate

UpregulatedGO.0002376Immune system process321
GO.0006952Defense response252
GO.0002682Regulation of immune system process246
GO.0006955Immune response241
GO.0050776Regulation of immune response175

DownregulatedGO.0007010Cytoskeleton organization109
GO.0016043Cellular component organization386
GO.0048522Positive regulation of cellular process362
GO.0051128Regulation of cellular component organization211
GO.0071840Cellular component organization or biogenesis390