Research Article

Identification of Key Pathways and Genes in Advanced Coronary Atherosclerosis Using Bioinformatics Analysis

Table 4

KEGG pathways enrichment analysis in networks.

Expression#Pathway IDPathway descriptionObserved gene countFalse discovery rate

Upregulated4380Osteoclast differentiation47
4060Cytokine-cytokine receptor interaction63
4062Chemokine signaling pathway51
4142Lysosome41
5150Staphylococcus aureus infection27

Downregulated4510Focal adhesion38
4810Regulation of actin cytoskeleton37
5412Arrhythmogenic right ventricular cardiomyopathy (ARVC)20
4921Oxytocin signaling pathway30
4022cGMP-PKG signaling pathway30