Identification of Key Pathways and Genes in Advanced Coronary Atherosclerosis Using Bioinformatics Analysis

Table 6

KEGG analysis based on module A.

GOID	GO term	Ontology source	Term value	Nr. genes	Associated genes found
GO:0004064	NF-kappa B signaling pathway	KEGG_01.03.2017		5.00	[CCL19, CCL21, CXCL12, CXCL2, CXCL8]
GO:0005150	Staphylococcus aureus infection	KEGG_01.03.2017		4.00	[C3, C3AR1, C5AR1, FPR3]
GO:0004060	Cytokine-cytokine receptor interaction	KEGG_01.03.2017		16.00	[CCL16, CCL19, CCL20, CCL21, CCL5, CCR1, CCR2, CCR5, CCR7, CXCL1, CXCL12, CXCL16, CXCL2, CXCL3, CXCL8, CXCR4]
GO:0004062	Chemokine signaling pathway	KEGG_01.03.2017		18.00	[ADCY3, ADCY4, CCL16, CCL19, CCL20, CCL21, CCL5, CCR1, CCR2, CCR5, CCR7, CXCL1, CXCL12, CXCL16, CXCL2, CXCL3, CXCL8, CXCR4]
GO:0004657	IL-17 signaling pathway	KEGG_01.03.2017		5.00	CCL20, CXCL1, CXCL2, CXCL3, CXCL8]
GO:0004668	TNF signaling pathway	KEGG_01.03.2017		5.00	CCL20, CCL5, CXCL1, CXCL2, CXCL3]
GO:0005120	Epithelial cell signaling in Helicobacter pylori infection	KEGG_01.03.2017		3.00	CCL5, CXCL1, CXCL8]
GO:0005132	Salmonella infection	KEGG_01.03.2017		4.00	CXCL1, CXCL2, CXCL3, CXCL8]
GO:0005134	Legionellosis	KEGG_01.03.2017		5.00	C3, CXCL1, CXCL2, CXCL3, CXCL8]
GO:0005323	Rheumatoid arthritis	KEGG_01.03.2017		5.00	CCL20, CCL5, CXCL1, CXCL12, CXCL8]