Reversal of Proximal Renal Tubular Dysfunction after Nucleotide Analogue Withdrawal in Chronic Hepatitis B

Table 1

Baseline data of CHB patients with nucleotide analogue-related proximal renal tubular dysfunction (PRTD).

Characteristics
Median age [IQR] (years)	61.0 [59–66]
Male, (%)	8 (50)
Cirrhosis, (%)	3 (18.8)
HBeAg positive, (%)	6 (37.5)
Hypertension, (%)	3 (18.8)
Diabetes, (%)	1 (6.2)
Median duration of nucleotide analogue [IQR] (months)	70.0 [49–75]
Type of nucleotide analogue, (%)
(i) Tenofovir or tenofovir +	10 (62.5)
(ii) Adefovir or adefovir + lamivudine	6 (37.5)
Severity of PRTD, (%)
(i) Subclinical	8 (50)
(ii) Overt	8 (50)

Six patients received adefovir. IQR, interquartile range.