Pediatric Multiple Sclerosis in Tunisia: A Retrospective Study over 11 Years

Table 1

Demographic and clinical findings in our series.

	Gender	Age of onset (years)	Family history	Medical history	Inaugural symptoms	Clinical manifestations on first attack, EDSS score
Patient 1	F	17	Goitre	None	Dysarthria + weakness of lower limbs + numbness in upper limbs	Thermic hyperesthesia + tactile hypoesthesia + upper limb dystonia + cerebellar ataxia. EDSS = 3.5
Patient 2	F	16	Epilepsy	Allergic rhinitis	Facial paralysis + diplopia + dizziness	6th nerve paralysis + tetrapyramidal syndrome + vestibular syndrome + cerebellar ataxia. EDSS = 3
Patient 3	F	3	None	None	Dysarthria + gait disorder	Dysarthria + static and kinetic cerebellar syndrome. EDSS = 3
Patient 4	M	10	None	None	Seizures + altered consciousness + gait disorder + decreased vision + vomiting	Dysarthria + dystonia + cerebellar syndrome + proprioceptive dysfunction + nystagmus + 7th nerve paralysis + decreased vision. EDSS = 2
Patient 5	F	17	None	Type 1 diabetes	Decreased vision + sphincter dysfunction + weakness and numbness of lower limbs	Paraparesis + pyramidal syndrome + cerebellar syndrome + proprioceptive dysfunction. EDSS = 4.5
Patient 6	M	10	None	Type 1 diabetes	Right hemibody weakness + paresthesia	Right hemiplegia. EDSS = 5
Patient 7	F	17	Bipolar disorder	None	Left hemibody weakness + paresthesia	Left hemiparesis + tactile and pain sensory dysfunction. EDSS = 3.5
Patient 8	M	4	None	Asthma	Headache + left hemibody weakness + hand movement disorder + vomiting	Left hemiparesis + central facial paralysis + hand dystonia. EDSS = 3.5
Patient 9	F	16	None	None	Left upper limb weakness + paresthesia	Left pyramidal syndrome + hemibody hypoesthesia + sensory level C4. EDSS = 2
Patient 10	F	14	None	None	Dizziness + cervical movement disorder + vomiting	Cervical dystonia + pyramidal syndrome + vestibular syndrome + paraparesis. EDSS = 4
Patient 11	M	12	None	None	Dizziness + vomiting + diplopia	Vestibular syndrome + pyramidal syndrome. EDSS = 1.5
Patient 12	F	15	None	None	Tremor of upper limbs + convergent strabismus + diplopia + urinary dysfunction	Dysarthria + right convergent strabismus + nystagmus + cerebellar syndrome. EDSS = 2
Patient 13	F	7	None	None	Gait disorder + hand movement disorder	Dystonia + myoclonus + tremor. EDSS = 3
Patient 14	F	17	None	Hypothyroidism	Lower limb weakness + hemibody paresthesia + facial paralysis + hand movement disorder	Spastic paraparesis + pyramidal syndrome + hemibody hypoesthesia. EDSS = 3
Patient 15	M	4.5	None	None	Hemibody weakness + facial paralysis	Right hemiparesis. EDSS = 2
Patient 16	F	12	None	None	Strabismus + facial paralysis + gait disorder + diplopia + dizziness + swallowing difficulties	Pseudobulbar syndrome + proprioceptive dysfunction. EDSS = 6
Patient 17	F	17	None	None	Four limbs weakness + paresthesia	Left lower limb paresis + thermic and pain sensory dysfunction + proprioceptive dysfunction. EDSS = 4.5
Patient 18	F	16	None	None	Paresthesia + tremor + facial paralysis + lower limb weakness	Right hemiparesis + tremor + kinetic cerebellar syndrome + pyramidal syndrome. EDSS = 2,5
Patient 19	F	4	None	None	Dysarthria + hemibody weakness	Spasmodic laughter and weeping + dysarthria + tetraparesis + cerebellar syndrome. EDSS = 4,5
Patient 20	F	8	None	None	Left hemibody weakness	Left hemiparesis. EDSS = 2
Patient 21	F	13	None	Type 1 diabetes	Paresthesia + hemibody weakness	Flaccid paraparesis + sensory level D3. EDSS = 4

EDSS: Expanded Disability Status Scale; F: female; M: male.