Impact of Fish Oil Supplementation and Interruption of Fructose Ingestion on Glucose and Lipid Homeostasis of Rats Drinking Different Concentrations of Fructose

Figure 5

Chronic fructose ingestion did not alter glucose tolerance or insulin sensitivity, and fish oil supplementation had no effect per se. The average blood glucose values during an oGTT (a, e), AUC for blood glucose values (b, f), blood glucose values during an ipITT (c, g), and (from 0 to 40 min) (d, h) in rats drinking water enriched with 10% fructose (w/v) (a–d) and 30% fructose (w/v) (e–h). Fructose ingestion lasted 9 consecutive weeks, and fish oil supplementation (1 g/Kg, b.m.) was introduced 30 days after the initiation of fructose ingestion and remained until the end of the ninth week. Results are expressed as mean ± SEM. ANOVA with Tukey’s post hoc test was applied and no differences among groups were achieved (–20). AUC: area under curve; : constant for glucose decay.