Jacalin Has Chemopreventive Effects on Colon Cancer Development

Figure 5

Jacalin treatment affects intestinal cytokine production. MNNG-exposed mice were treated with jacalin (0.5 and 25 μg) and proinflammatory and anti-inflammatory cytokine levels in colon homogenates were determined by ELISA. Jacalin treatment led to a significant increase in TNF and TGF-β1 levels in colonic tissue. Results are expressed as mean ± SEM for each group. Statistical analysis: one-way analysis of variance. to control group; to PBS group. or ; and .