Liver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-κB and JNK/p38 MAPK Signal Pathways

Figure 1

Effects of TO901317 on lung W/D ratio and histopathological changes in lung tissues. The lung W/D ratio (a) and lung histological evaluation (b, c, HE staining, 200x) were determined 72 h after PQ administration. TO901317L: TO901317 at the low dose of 5 mg/kg; TO901317H: TO901317 at the high dose of 20 mg/kg. The values presented are the mean ± SD (). versus PQ group. versus PQ + TO901317L group.

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