Liver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-κB and JNK/p38 MAPK Signal Pathways

Figure 3

Effects of TO901317 on inflammatory cytokine release and MPO activity. BALF and lung tissues were collected after PQ administration for 6, 12, 24, and 72 h to analyze IL-1β (a), TNF-α (b), and MPO activity (c). TO901317L: TO901317 at the low dose of 5 mg/kg; TO901317H: TO901317 at the high dose of 20 mg/kg. The values presented are the mean ± SD (). versus PQ group. versus PQ + TO901317L group.

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