Research Article

Liver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-κB and JNK/p38 MAPK Signal Pathways

Figure 6

Effect of T0901317 on JNK/p38 MAPKs signal pathway in lung tissues of mice. Lung tissues were collected after PQ administration for 72 h to determine the expression of p-p38 (a, b, c, d) and p-JNK (e, f, g, h) by Western blot and immunohistochemistry. TO901317L: TO901317 at the dose of 5 mg/kg; TO901317H: TO901317 at the dose of 20 mg/kg. The values presented are the mean ± SD (). versus PQ group; versus PQ + TO901317L group.