Design, Development, and Optimization of Dexibuprofen Microemulsion Based Transdermal Reservoir Patches for Controlled Drug Delivery

Figure 2

Physical characterization of droplet size of ME by DLS. (a) Dynamic Light Scattering results of freshly prepared F5_ME illustrating the experimental conditions, that is, the mean autocorrelation function, monodispersity, and the radius plots (A) to (C), respectively. (b) Mean corresponding radius of hydration and percent polydispersity followed till 6 hrs clearly revealed increase in radius and polydispersity. All experiments were performed with an autopiloted run of 50 measurements at every 20 s, with a wait time between of 1 s (at 25°C). See Table 3 for details.

(a)

(b)