Design, Development, and Optimization of Dexibuprofen Microemulsion Based Transdermal Reservoir Patches for Controlled Drug Delivery

Table 1

Solubility of dexibuprofen in various vehicles.

Vehicle	Solubility (g/mL)
Ethyl oleate	0.182 ± 0.011
Surfactants
Tween 40	0.165 ± 0.019
Tween 60	0.126 ± 0.023
Tween 80	0.306 ± 0.006
Triethanolamine	0.109 ± 0.013
Cosurfactants
Propylene glycol	0.209 ± 0.026
Polyvinyl alcohol	0.133 ± 0.019
PEG 400	0.123 ± 0.012
Ethanol	0.105 ± 0.029
Oily mixture	0.536 ± 0.013