Design, Development, and Optimization of Dexibuprofen Microemulsion Based Transdermal Reservoir Patches for Controlled Drug Delivery

Table 5

Permeation parameters of formulations F1–F6 of dexibuprofen reservoir patches.

Formulations	Lag time; ()	Permeability; coefficient	Diffusion coefficient ()			Best fit equation for; permeation plot	Regression; coefficient
	h	cm/h	cm^2/h
F1	0.42			0.953	0.047	= 209.15 + 87.9	0.9954
F2	1.56			0.974	0.026	= 227.52 + 1.56	0.9894
F3	1.59			0.956	0.044	= 210.55 + 334.99	0.9669
F4	0.46			0.780	0.220	= 309.72  − 141.12	0.9983
F5	1.33			0.861	0.139	= 331.17 + 439.73	0.9939
F6	2.15			0.941	0.059	= 213.69 + 458.84	0.9710