Glucose-Insulin-Potassium Alleviates Intestinal Mucosal Barrier Injuries Involving Decreased Expression of Uncoupling Protein 2 and NLR Family-Pyrin Domain-Containing 3 Inflammasome in Polymicrobial Sepsis

Figure 3

Effects of GIK on histopathological changes in ileum tissues in CLP-induced polymicrobial rats. Ileum tissues were carried out for histological evaluation at 24 hours after CLP in first set of rats. Representative H&E staining histological changes of ileum harvested from rats of different groups. (a) Control group, (b) sham CLP group, (c) CLP group, (d) CLP + GIK group, and (e) CLP + GK group (hematoxylin and eosin staining, magnification 40x). (f) shows Chiu’s scoring of mucosal injury of each experimental group ( in each analysis) of no less than six independent experiments ( versus sham CLP group, versus CLP group, and versus CLP + GIK group by the chi-square test for trend).