Novel Mutations and Mutation Combinations of<i> TMPRSS3</i> Cause Various Phenotypes in One Chinese Family with Autosomal Recessive Hearing Impairment

<div>Conservation analysis of residues<i> TMPRSS3 </i>in family FH1523. Protein alignment showing conservation of residues TMPRSS3 Ala306, Phe13, and Arg106 across nine species. Three mutations all occurred at evolutionarily conserved amino acids (in red box).</div>

BioMed Research International

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Figure 3: Novel Mutations and Mutation Combinations of<i> TMPRSS3</i> Cause Various Phenotypes in One Chinese Family with Autosomal Recessive Hearing Impairment 

Figure 3 | Novel Mutations and Mutation Combinations of TMPRSS3 Cause Various Phenotypes in One Chinese Family with Autosomal Recessive Hearing Impairment 