Curcumin Analogue CA15 Exhibits Anticancer Effects on HEp-2 Cells via Targeting NF-κB

Table 2

The IC₅₀ values of compounds towards HEp-2 and HL-7702 cells.

Group	HEp-2 (μM)	HL-7702 (μM)
Curcumin	21.37 ± 3.25	32.33 ± 6.21
CA15	16.59 ± 2.43	46.79 ± 8.77
EF24	14.09 ± 5.32
B19	11.69 ± 2.66	15.19 ± 2.76
BMS-345541		23.63 ± 3.24

HEp-2 and HL-7702 cells were treated with different concentrations (0–60 μM) of compounds for 72 h and then tested with MTT assay. Data are presented as means ± SEM of 3 independent experiments. < 0.05 versus curcumin group.