Research Article
MicroRNA Expression Signature in Human Calcific Aortic Valve Disease
Table 1
Fifty-three underexpressed and 39 overexpressed miRNAs in aortic tissue from CAVD patients compared to the control group.
| Systematic name | value | Fold change | Regulation |
| hsa-miR-3656 | 0.011202 | 2.0143232 | Up | hsa-miR-765 | 0.033639 | 2.0401733 | Up | hsa-miR-2861 | 0.008741 | 2.0782373 | Up | hsa-miR-663a | 0.00633 | 2.0819619 | Up | hsa-miR-1246 | 0.027045 | 2.1549542 | Up | hsa-miR-3141 | 0.002969 | 2.2772849 | Up | hsa-miR-125a-3p | 0.012002 | 2.3428166 | Up | hsa-miR-4327 | 0.004807 | 2.367507 | Up | hsa-miR-638 | 0.002785 | 2.3686504 | Up | hsa-miR-4270 | 0.030574 | 2.4421182 | Up | hsa-miR-642b-3p | 0.034575 | 2.5763547 | Up | hsa-miR-513a-5p | 0.007538 | 2.6546612 | Up | hsa-miR-483-5p | 0.008099 | 2.655595 | Up | hsa-miR-3679-5p | 0.004016 | 2.7413363 | Up | hsa-miR-3648 | 0.017053 | 2.8097122 | Up | hsa-miR-30c-1-3p | 7.64E-04 | 2.893416 | Up | hsa-miR-1275 | 0.005457 | 2.9556682 | Up | hsa-miR-513b | 0.020604 | 3.4257321 | Up | hsa-miR-1972 | 0.011389 | 3.689852 | Up | hsa-miR-3138 | 0.004076 | 3.974949 | Up | hsa-miR-3663-3p | 0.005874 | 4.314916 | Up | hsa-miR-21-5p | 0.003826 | 4.317176 | Up | hsa-miR-718 | 0.031718 | 4.957687 | Up | hsa-miR-630 | 0.001304 | 7.3841376 | Up | hsa-miR-575 | 0.001586 | 10.079804 | Up | hsa-miR-3934 | 0.048827 | 13.458452 | Up | hsa-miR-143-5p | 0.033632 | 16.2909 | Up | hsa-miR-3131 | 0.047501 | 22.065104 | Up | hsa-miR-125b-1-3p | 0.00519 | 23.412596 | Up | hsa-miR-625-3p | 0.005867 | 23.648891 | Up | hsa-miR-1471 | 0.035145 | 25.31259 | Up | hsa-miR-4314 | 0.032125 | 27.92129 | Up | hsa-miR-636 | 0.00923 | 28.36478 | Up | hsa-miR-3945 | 0.018336 | 38.864952 | Up | hsa-miR-3610 | 0.014352 | 49.196358 | Up | hsa-miR-1182 | 1.46E-05 | 73.30232 | Up | hsa-miR-3713 | 2.44E-05 | 117.90961 | Up | hsa-miR-21-3p | 5.95E-05 | 149.08258 | Up | hsa-miR-516a-5p | 2.88E-05 | 155.79349 | Up | hsa-miR-654-3p | 0.002559 | 2.0230756 | Down | hsa-miR-93-5p | 0.020279 | 2.0238087 | Down | hsa-miR-320d | 0.038247 | 2.052202 | Down | hsa-miR-381 | 0.035566 | 2.0584567 | Down | hsa-miR-214-3p | 0.011756 | 2.0957778 | Down | hsa-miR-125b-5p | 0.036771 | 2.1063256 | Down | hsa-miR-361-3p | 0.036059 | 2.1256602 | Down | hsa-miR-29c-3p | 0.009743 | 2.1358023 | Down | hsa-miR-495 | 0.001289 | 2.1425073 | Down | hsa-miR-374a-5p | 0.01904 | 2.1439137 | Down | hsa-miR-20b-5p | 0.027368 | 2.1694279 | Down | hsa-miR-382-5p | 0.043289 | 2.1756916 | Down | hsa-miR-4324 | 0.039752 | 2.178068 | Down | hsa-miR-25-3p | 0.004579 | 2.1911306 | Down | hsa-miR-100-5p | 0.035509 | 2.1913323 | Down | hsa-miR-193b-3p | 0.022676 | 2.191656 | Down | hsa-miR-107 | 0.007782 | 2.2016506 | Down | hsa-miR-660-5p | 8.68E-04 | 2.2094207 | Down | hsa-miR-103a-3p | 0.020178 | 2.2370007 | Down | hsa-miR-195-5p | 0.049708 | 2.3292358 | Down | hsa-miR-299-5p | 0.002066 | 2.3574395 | Down | hsa-miR-487b | 7.71E-04 | 2.422462 | Down | hsa-miR-128 | 0.022531 | 2.4691415 | Down | hsa-miR-181d | 0.019566 | 2.5412066 | Down | hsa-miR-374b-5p | 0.038373 | 2.5474217 | Down | hsa-let-7b-5p | 0.042981 | 2.6197023 | Down | hsa-miR-140-5p | 0.005972 | 2.639281 | Down | hsa-let-7g-5p | 0.02818 | 2.7145965 | Down | hsa-miR-151a-5p | 0.010444 | 2.7681546 | Down | hsa-miR-532-5p | 0.020008 | 2.7994845 | Down | hsa-miR-26b-5p | 0.025414 | 2.8088717 | Down | hsa-miR-30e-3p | 0.020305 | 2.8739653 | Down | hsa-miR-140-3p | 0.040144 | 2.8943768 | Down | hsa-miR-29c-5p | 0.004665 | 2.9975233 | Down | hsa-miR-181c-5p | 0.015322 | 3.0353231 | Down | hsa-miR-204-5p | 0.044941 | 3.0471704 | Down | hsa-let-7d-5p | 0.025658 | 3.0987353 | Down | hsa-miR-98 | 0.027495 | 3.2012997 | Down | hsa-miR-10a-5p | 0.019225 | 3.3482268 | Down | hsa-let-7f-5p | 0.037282 | 3.4332418 | Down | hsa-let-7e-5p | 0.018337 | 3.6489105 | Down | hsa-let-7a-5p | 0.029403 | 3.6912477 | Down | hsa-miR-99a-5p | 0.035923 | 3.8172672 | Down | hsa-let-7c | 0.032672 | 3.9863558 | Down | hsa-miR-126-3p | 0.026073 | 4.528461 | Down | hsa-miR-29b-1-5p | 0.006566 | 15.589992 | Down | hsa-miR-181c-3p | 0.008219 | 16.225191 | Down | hsa-miR-194-5p | 0.011511 | 20.940771 | Down | hsa-miR-335-5p | 0.006273 | 36.750603 | Down | hsa-miR-126-5p | 0.015298 | 38.692142 | Down | hsa-miR-505-5p | 1.18E-05 | 42.592148 | Down | hsa-miR-625-5p | 0.008835 | 43.434204 | Down | hsa-miR-200b-3p | 1.60E-06 | 70.24472 | Down |
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