Oxidative Modification of Biomolecules in the Nonstimulated and Stimulated Saliva of Patients with Morbid Obesity Treated with Bariatric Surgery

Table 2

Comparison of oxidative damage products in unstimulated and stimulated saliva of patients with morbid obesity before and after bariatric surgery as well as healthy controls.

	C		O		ABS
	NS	S	NS	S	NS	S
4-HNE; (μg/100 mg of protein)	34.62 ± 8.80	49.72 ± 8.34	39.49 ± 6.92	66.17 ± 15.38	34.16 ± 7.94	52.22 ± 9.85
	8-isoP; (pg/100 mg of protein)	4.65 ± 1.71	3.30 ± 0.90	14.76 ± 5.41	13.05 ± 3.14	12.80 ± 4.74	10.63 ± 2.12
AOPP; (μmol/100 mg of protein)		2.07 ± 1.59	1.16 ± 0.69	7.80 ± 11.37	6.45 ± 13.07	2.28 ± 1.06	1.56 ± 0.75
	PC; (nmol/100 mg of protein)	253.31 ± 103.25	282.76 ± 185.58	1579.51 ± 403.26	1164.21 ± 454.74	314.07 ± 104.20	398.32 ± 100.54
8-OHdG; (ng/100 mg of protein)		0.43 ± 0.19	0.40 ± 0.16	1.14 ± 0.83	1.77 ± 1.34	0.47 ± 0.22	0.63 ± 0.18

C, control; O, morbid obese patients; ABS, patients after the bariatric surgery; NS, unstimulated whole saliva; S, stimulated whole saliva; 4-HNE protein adducts; 4-hydroxynonenal protein adducts; 8-isoP, 8-isoprostanes; AOPP, advanced oxidation protein products; PC, protein carbonyl groups; 8-OHdG, 8-hydroxy-D-guanosine.