NLRP1 Overexpression Is Correlated with the Tumorigenesis and Proliferation of Human Breast Tumor

Table 2

Association of NLRP1 expression and clinic-pathological parameters of 72 breast cancer patients.

Characteristics		NLRP1 expression		value
		Low expression	High expression
Total	72	12	60
Age (years)				0.343
<55	36	4	32
≥55	36	8	28
Tumor size (cm)				0.197
≤2.5	24	6	18
>2.5	48	6	42
Lymph node metastasis				0.003
No	30	10	20
Yes	42	2	40
Histological grade				1
I/II	37	6	31
III	35	6	29
TNM stage				0.003
I/II	20	8	12
III/IV	52	4	48
ER				0.117
Negative	32	8	24
Positive	40	4	36
PR				1
Negative	34	6	28
Positive	38	6	32
HER2				0.744
Negative	22	3	19
Positive	50	9	41
P53				0.43
Negative	36	4	32
Positive	36	8	28
Ki-67				<0.001
Negative	12	10	2
Positive	60	2	58

Estrogen receptor (ER); progesterone receptor (PR).