Obesity Induces Artery-Specific Alterations: Evaluation of Vascular Function and Inflammatory and Smooth Muscle Phenotypic Markers

Figure 2

Modulation of contractile response by nitric oxide and prostanoids in obese mice. Concentration-response curves to noradrenaline in the absence and presence of inhibitors of nitric oxide synthase (L-NAME), inducible nitric oxide synthase (L-NIL), and cyclooxygenase (indomethacin) in small arteries (a, b, and c) and thoracic aorta (d, e, and f) from control and obese mice. Data are expressed as mean ± SEM. –12.

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