Obesity Induces Artery-Specific Alterations: Evaluation of Vascular Function and Inflammatory and Smooth Muscle Phenotypic Markers

Figure 4

Vascular smooth muscle phenotype markers in arteries of obese mice. mRNA levels of SM22α, Notch3, α-actin, α-actinin, caldesmon (Cald), tropomyosin (Tropom), and myosin light chain kinase (MLCK) in small mesenteric arteries (a) and thoracic aorta (b) from control and obese mice. Expression levels of specific gene mRNA were normalized to the cyclophilin mRNA. Data are expressed as mean ± SEM. Unpaired -test: versus control mice. –10.

(a)

(b)