The Critical Role of Long Noncoding RNA in Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells

<div>(a) The expression level of lncRNA ENST00000502125.2 was decreased during osteogenic differentiation of hBMmSCs. (b) ShRNA could significantly downregulate lncRNA ENST00000502125.2 expression. (c) Lentivirus vectors could significantly upregulate lncRNA ENST00000502125.2 expression. (d) Downregulation of lncRNA ENST00000502125.2 promoted the ALP staining intensity, and vice versa (200x). 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BioMed Research International

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Figure 5

Figure 5: The Critical Role of Long Noncoding RNA in Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells 