Weekday of Surgery Affects Postoperative Complications and Long-Term Survival of Chinese Gastric Cancer Patients after Curative Gastrectomy

Table 4

Multivariate Cox regression analysis of overall and disease-free survival in 463 patients after gastrectomy.

Characteristics	Overall survival		Disease-free survival
	HR (95% CI)	p value	HR (95% CI)	p value
Comorbidities (with/without)	—	—	0.886 (0.636–1.233)	0.472
Tumor size (≥5 cm/<5 cm)	—	—	1.055 (0.766–1.453)	0.741
Operation time (≥240 min/<240 min)	0.869 (0.582–1.299)	0.494	0.770 (0.520–1.139)	0.191
Operative blood loss (≥500 ml/<500 ml)	1.023 (0.691–1.514)	0.909	0.968 (0.662–1.417)	0.869
T classification		0.017		0.018
(T2/T1)	2.315 (0.902–5.945)	0.081	1.517 (0.670–3.433)	0.318
(T3/T1)	3.691 (1.373–9.921)	0.010	2.528 (1.062–6.020)	0.036
(T4/T1)	4.001 (1.231–13.007)	0.021	2.677 (0.920–7.789)	0.071
N classification		<0.001		<0.001
(N1/N0)	1.790 (1.350–2.374)	<0.001	1.988 (1.515–2.608)	<0.001
(N2/N0)	1.953 (1.144–3.333)	0.014	2.510 (1.515–4.157)	<0.001
(N3/N0)	2.838 (1.325–6.078)	0.007	2.954 (1.422–6.138)	0.004
TNM stage		0.016		0.005
(II/I)	1.182 (0.674–2.075)	0.560	1.118 (0.654–1.912)	0.684
(III/I)	2.520 (1.078–5.894)	0.033	2.536 (1.114–5.773)	0.027
Postoperative complications (with/without)	3.169 (2.388–4.204)	<0.001	2.826 (2.134–3.740)	<0.001
Weekday (late/early)	1.721 (1.343–2.205)	<0.001	1.693 (1.331–2.153)	<0.001
Chemotherapy (no/yes)	1.087 (0.830–1.423)	0.546	1.204 (0.928–1.562)	0.161
Increased postoperative CRP (yes/no)	1.399 (1.042–1.879)	0.026	1.533 (1.150–2.045)	0.004