Structure and Function of Trypsin-Loaded Fibrinolytic Liposomes

Figure 3

Lysis of fibrin by layered on the clot surface or homogeneously dispersed in the clots. The liposomal solution was layered over preformed clots (a) or added to fibrinogen before the clotting phase (b) and thereafter formation and/or dissolution of fibrin were followed as changes in absorbance at 340 nm shown as mean (solid lines) ± SEM (dotted lines) of three measurements. Red and blue colours indicate clot lysis at 45°C and 37°C, respectively.

(a)

(b)