Research Article

Structure and Function of Trypsin-Loaded Fibrinolytic Liposomes

Table 1

Lysis times needed to dissolve fibrin clots by 20, 50, or 80%. Mean values ± SEM are shown (). Asterisk indicates statistical significance between the values measured at the two temperatures at according to Kolmogorov-Smirnov test.

(min) (min) (min)

Extrinsic lysis
 37°C21.23 ± 6.9689.75 ± 13.50190.16 ± 9.02
 45°C42.99 ± 6.6472.77 ± 14.71167.71 ± 17.80
Intrinsic lysis
 37°C131.44 ± 4.39165.80 ± 4.70192.24 ± 5.06
 45°C133.71 ± 1.15156.41 ± 2.08