Identification of IFITM1 and IFITM3 in Goose: Gene Structure, Expression Patterns, and Immune Reponses against Tembusu Virus Infection

Figure 3

Multiple alignment analysis of IFITM1 and IFITM3 amino acid sequences. The amino acid sequences from goose, duck, chicken, mouse, and human were subjected to multiple alignment analysis using ClustalW. The proteins each consist of an N-terminal domain (NTD), transmembrane domain 1 (TM1), conserved intracellular loop (CIL), transmembrane domain 2 (TM2), and C-terminal domain (CTD). The blue highlights the YxxΦ motifs, which are absent in IFITM1. The two palmitoylated cysteines and three lysines serving as ubiquitination sites are indicated with pink and green, respectively.