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BioMed Research International
Volume 2017, Article ID 5178631, 12 pages
Review Article

Valve Calcification in Aortic Stenosis: Etiology and Diagnostic Imaging Techniques

1Department of Cardiology, Hospital Universitario de Canarias, Tenerife, Spain
2Servicios Sanitarios del Área de Salud de El Hierro, Valle del Golfo Health Center, El Hierro, Spain

Correspondence should be addressed to Juan Lacalzada-Almeida; moc.liamg@adazlacalj

Received 5 April 2017; Accepted 20 June 2017; Published 24 July 2017

Academic Editor: Giacomina Brunetti

Copyright © 2017 María Manuela Izquierdo-Gómez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aortic stenosis is the most common valvulopathy in the Western world. Its prevalence has increased significantly in recent years due to population aging; hence, up to 8% of westerners above the age of 84 now have severe aortic stenosis (Lindroos et al., 1993). This causes increased morbidity and mortality and therein lies the importance of adequate diagnosis and stratification of the degree of severity which allows planning the best therapeutic option in each case. Long understood as a passive age-related degenerative process, it is now considered a rather more complex entity involving mechanisms and factors similar to those of atherosclerosis (Stewart et al., 1997). In this review, we summarize the pathophysiological mechanisms underlying the onset and progression of the disease and analyze the current role of cardiac imaging techniques for diagnosis.