Research Article

Elevated Foxp3/CD8 Ratio in Lung Adenocarcinoma Metastatic Lymph Nodes Resected by Transcervical Extended Mediastinal Lymphadenectomy

Table 2

Proportion of CD8+, CD25+, and Foxp3+ cells in the lymph nodes resected by TEMLA of patients with squamous cell type (SCC) lung cancer and lung adenocarcinoma (AD) with (+) and without (−) detected metastases. Data expressed as median value, (p25–p75). difference between groups A and B in Mann-Whitney test, .

CD8+ 
CD25+ 
Foxp3+ 

A
(AD +)

50–60
12.5 
10–22,5
20 
11–30
B
(AD −)

60–80
12 
10–30
20 
15–25
A
(SCC +)
65 
50–80
25 
15–30
23.5 
11–30
B
(SCC −)
60 
50–65
10 
10–20
30 
18–40
Intensity+++/++++/++++/+