Deviation of the Fecal Stream in Colonic Bowel Segments Results in Increased Numbers of Isolated Lymphoid Follicles in the Submucosal Compartment in a Novel Murine Model of Diversion Colitis

Figure 2

Causes of death. Postoperative complications were determined by necropsy. Wasting syndrome was defined as continuous weight loss greater than 33% of the initial body weight and no other findings on necropsy. Ileus and anastomotic leakage were diagnosed on necropsy. Stoma complications were defined as peristomal abscess and mucocutaneous separation. There were significant differences in the distribution of postoperative complications in between all groups (comparison of all groups: ; comparison of only PC and DC: ; comparison of only PC and sham: ; comparison of only DC and sham: ), analyzed by Fisher’s exact test for two-sided analysis of up to 6 × 6 contingency tables. Animal numbers were 39 in the PC and DC group, respectively, and 29 in the sham group.