Computational Exploration for Lead Compounds That Can Reverse the Nuclear Morphology in Progeria

Table 2

Different parameters computed by decoy set method. The GF score confirms the predictive ability of the pharmacophore.

S. number	Parameters	Values
	Total number of molecules in database ()	107
	Total number of actives in database ()	9
	Total number of Hit molecules from the database (Ht)	9
	Total number of active molecules in Hit list (Ha)	8
	% yield of active (Ha/Ht)	88.8
	% ratio of actives [(Ha/) × 100]	88
	Enrichment factor (EF)	9.4
	False negatives	1
	False positives	1
	Goodness of fit score (GF)	0.71

GH = and .