Computational Exploration for Lead Compounds That Can Reverse the Nuclear Morphology in Progeria

Table 5

HOMO, LUMO, and band gap of the Hits and the reference compounds computed employing the DFT approach.

Name	HOMO; (eV)	LUMO; (eV)	Band gap; (eV)
Reference	−0.163	−0.0547	0.108
Hit 1	−0.154	−0.095	0.058
Hit 2	−0.179	−0.1149	0.064
Lonafarnib	−0.182	−0.0766	0.105