Robust Significance Analysis of Microarrays by Minimum β-Divergence Method

Table 4

Performance evaluation of different methods for detection of up- and downregulated genes in 6 pairs with conditions for small-sample case ().

Methods	Pairwise comparison
	1vs2	1vs3	1vs4	2vs3	2vs4	3vs4
	In absence of outliers
True (UR, DR)	(100, 30)	(100, 120)	(100, 50)	(30, 120)	(30, 50)	(120, 50)
ANOVA
	SAM
LIMMA
	KW
Proposed
		In presence of one outlier with each of 10% genes
True (UR, DR)	(100, 30)	(100, 120)	(100, 50)	(30, 120)	(30, 50)	(120, 50)
ANOVA
	SAM
LIMMA
	KW
Proposed

In this table the values within the bracket represent the number of true up- and downregulated (UR, DR) DE genes in 6 pairs and the values within the brackets and represent the number of predicted (UR, DR) genes by five methods (ANOVA, KW, SAM, LIMMA, and proposed) and correctly detected number of (UR, DR) DE genes by these methods in both absence and presence of one outlier with each of 10% genes.