Research Article
MicroRNA-31 Function as a Suppressor Was Regulated by Epigenetic Mechanisms in Gastric Cancer
Figure 6
miR-31 promoter was hypermethylated in gastric cancer. The genome DNA was extracted from gastric cancer tissue (a) or cell lines (b); the methylation level of miR-31 promoter was detected using bisulfite sequencing PCR. (c) The total RNA was extracted from gastric cancer tissue; the expression of DNMT1, 3A, and 3B was measured by qRT-PCR , , and .
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