Comparison of DNA Methylation in Schwann Cells before and after Peripheral Nerve Injury in Rats
Table 4
Calculating CpG enrichment of provided short reads compared to the reference genome.
Class
CpGs number
CpGs rel. frequency (%)
CpGs obs/exp
Enrichment rel. frequency (%)
Enrichment obs/exp
BSgenome.Rnorvegicus.UCSC
24713205
0.851414595
0.247437644
—
—
ASCs_1
73092752
2.01814666
0.393297098
2.37034539
1.589479639
ASCs_2
66573452
1.986667228
0.38941539
2.333372296
1.57379202
ASCs_3
56781764
2.026584608
0.394905638
2.380255893
1.595980428
NSCs_1
68221902
1.916242372
0.381639103
2.25065718
1.542364761
NSCs_2
62275625
1.922886765
0.382886143
2.258461126
1.547404574
NSCs_3
67670669
1.982610575
0.391849804
2.328607692
1.583630515
rel: relative; obs: observed; exp: expected; ASCs: activated Schwann cells; NSCs: normal Schwann cells. All statistics of calculations and plot are using MEDIPS, R package for MeDIP-Seq. BSgenome, Rnorvegicus, and UCSC were all genome databases.
