BioMed Research International / 2017 / Article / Tab 3

Research Article

Susceptibility of In Vitro Melanoma Skin Cancer to Photoactivated Hypericin versus Aluminium(III) Phthalocyanine Chloride Tetrasulphonate

Table 3

LDH membrane integrity assay to evaluate PDT effect of Hyp and AlPcS4Cl.

Cells + no PS, no LICells +
2,5 µM PS
Cells +
5 J/cm2
Cells +
2,5 µM PS + 1 J/cm2
Cells +
2,5 µM PS
+ 2.5 J/cm2
Cells +
2,5 µM PS + 5 J/cm2
Cells +
2,5 µM PS
+ 10 J/cm2

AlPcS4Cl
1 hr0.460
± 0.039
0.470
± 0.026
0.386
± 0.026
0.485
± 0.031
0.494
± 0.024
0.492
± 0.029
0.507
± 0.031
4 hrs0.476
± 0.016
0.489
± 0.014
0.445
± 0.026
0.500
± 0.014
0.525
± 0.016
0.545
± 0.020
0.534
± 0.028
24 hrs0.407
± 0.018
0.448
± 0.014
0.360
± 0.017
0.412
± 0.024
0.515
± 0.035
0.524
± 0.036
0.535
± 0.036

Hyp
1 hrs0.453
± 0.017
0.467
± 0.017
0.428
± 0.020
0.475
± 0.017
0.482
± 0.016
0.495
± 0.018
0.562
± 0.045
4 hrs0.431
± 0.012
0.445
± 0.011
0.403
± 0.018
0.461
± 0.013
0.471
± 0.013
0.527
± 0.033
0.539
± 0.035
24 hrs0.450
± 0.006
0.480
± 0.009
0.438
± 0.009
0.496
± 0.010
0.500
± 0.011
0.527
± 0.010
0.566
± 0.030

; LDH: Lactate Dehydrogenase; LI: laser irradiation; PS: photosensitizer; ; ; ±SE.

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