Relationship between Interferon Beta-1A Administration and Intracranial Vascular Tone Regulation in Patients with Relapsing-Remitting Multiple Sclerosis: A Pilot Study
Table 3
Intra- and intergroup differences at T0-T1 in headache and no-headache multiple sclerosis (MS) groups.
Headache MS group Median (first-third quartile)
No-headache MS group Median (first-third quartile)
value (U Mann–Whitney)
HR T0
81 (76–88.5)
77 (72.5–82.5)
0.26
HR T1
83 (77.5–90)
77 (73.5–78.5)
0.10
value (Wilcoxon)
0.62
1.00
SBP T0
122.5 (115–130)
117.5 (110–125)
0.37
SBP T1
120 (117.5–125)
115 (110–121.25)
0.31
value (Wilcoxon)
1.00
0.52
DBP T0
80 (75–81.25)
75 (70–80)
0.17
DBP T1
80 (78.75–81.25)
72.5 (70–80)
0.07
value (Wilcoxon)
1.00
0.42
MFV-ICA T0
47 (45.5–49.75)
51 (49.75–53.5)
0.06
MFV-ICA T1
51 (48–53)
52.5 (48–53.25)
0.58
value (Wilcoxon)
0.44
MFV-MCA T0
58 (58–60.25)
60 (58.75–62.25)
0.29
MFV-MCA T1
63 (59.75–68)
60 (59–62.25)
0.27
value (Wilcoxon)
0.38
MFV-A1 ACA T0
45 (44.5–45.25)
45 (42.5–45.25)
0.60
MFV-A1 ACA T1
47 (45.5–50.25)
45 (44–46)
0.15
value (Wilcoxon)
0.10
MFV-PCA T0
40.5 (38.75–41.25)
40.5 (38.75–42)
0.78
MFV-PCA T1
42 (40–44.25)
41 (40–42.25)
0.38
value (Wilcoxon)
0.12
HR: heart ratio, SBP: systolic blood pressure; DBP: diastolic blood pressure; MFV-ICA: mean blood flow velocity internal carotid artery; MFV-MCA: mean blood flow velocity middle cerebral artery; MFV-A1 ACA: mean blood flow velocity section A1 of the anterior cerebral artery; MFV-PCA: mean blood flow velocity posterior cerebral artery. .
