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BioMed Research International
Volume 2017, Article ID 5436927, 9 pages
https://doi.org/10.1155/2017/5436927
Research Article

Quantitative Aortic Distensibility Measurement Using CT in Patients with Abdominal Aortic Aneurysm: Reproducibility and Clinical Relevance

1Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China
2Department of Thyroid and Breast Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Radiology, Huaihe Hospital of Henan University, Kaifeng, China
4Department of Biological Engineering, School of Biomedical Engineering, South-Central University for Nationalities, Wuhan, China
5Hubei Key Laboratory of Medical Information Analysis & Tumor Diagnosis and Treatment, Wuhan, China

Correspondence should be addressed to Liang Li; nc.ude.uhw@1800203029002

Received 22 January 2017; Revised 15 March 2017; Accepted 23 March 2017; Published 18 April 2017

Academic Editor: Christos V. Ioannou

Copyright © 2017 Yunfei Zha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To investigate the reproducibility of aortic distensibility () measurement using CT and assess its clinical relevance in patients with infrarenal abdominal aortic aneurysm (AAA). Methods. 54 patients with infrarenal abdominal aortic aneurysm were studied to determine their distensibility by using 64-MDCT. Aortic cross-sectional area changes were determined at two positions of the aorta, immediately below the lowest renal artery (level 1.) and at the level of its maximal diameter (level 2.) by semiautomatic segmentation. Measurement reproducibility was assessed using intraclass correlation coefficient (ICC) and Bland-Altman analyses. Stepwise multiple regression analysis was performed to assess linear associations between aortic and anthropometric and biochemical parameters. Results. A mean distensibility of and was found. ICC proved excellent consistency between readers over two locations: 0.92 for intraobserver and 0.89 for interobserver difference in level 1. and 0.85 and 0.79 in level 2. Multivariate analysis of all these variables showed sac distensibility to be independently related () to BMI, diastolic blood pressure, and AAA diameter. Conclusions. Aortic distensibility measurement in patients with AAA demonstrated high inter- and intraobserver agreement and may be valuable when choosing the optimal dimensions graft for AAA before endovascular aneurysm repair.