Mechanism of Reduced Susceptibility to Fosfomycin in Escherichia coli Clinical Isolates

Figure 2

Induced expression levels of uhpT expression by the addition of G6P. Nine clinical isolates with reduced susceptibility to FOM; six susceptible clinical isolates and one standard strain are included. Data used to generate this figure are given in Table 2. Statistical significance was determined by Mann–Whitney test. (a) Comparison of strains not grown (−) or strains grown (+) in M9 minimum salt solution containing G6P. (b) Comparison of strains with FOM MIC ≥ 8 μg/mL or ≤4 μg/mL.

(a)

(b)