Sertraline Induces Toxicity and Behavioral Alterations in Planarians

Figure 3

Planarian seizure-like activity evoked by sertraline. The planarian images were made after 24 h of exposure to 1 µM sertraline ((a) and (b)) and 4 µM sertraline ((c) and (d)). The asynchronous paroxysms C-like position ((a) and (c)) and screw-like hyperkinesia ((b) and (d)) were observed for both sertraline concentrations.

(a)

(b)

(c)

(d)